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Congratulations to CMB Trainer, Robert Landick, on being elected to the American Academy of Arts and Sciences! Those previously recognized by the Academy include Martin Luther King Jr., Charles Darwin, and many more. Read the full article from UW News.

Congratulations to CMB student, Amelia Haj, on being chosen for the Fellowships at Auschwitz for the Study of Professional Ethics (FASPE). This is a two-week program in Germany and Poland examining the conduct of physicians in Nazi-occupied Europe to reflect on medical ethics today. Read more about the Fellowship here.

Congratulations to CMB Trainer, Qiang Chang, on being named the new director of the Waisman Center! He will assume the position on July 1. Chang joined the UW-Madison faculty in 2007. His research interests focus on Rett syndrome. Read the full story from UW News here.

Congratulations to three CMB students on their NSF Fellowship Awards! Katherine Mueller (Saha Lab) and Mitchell Ledwith (Mehle Lab) were both awarded the NSF Graduate Research Fellowship and Ani Varjabedian (Bement Lab) was awarded Honorable Mention. You can see the full list of UW-Madison awardees here.

Congratulations to the 2017 winners of the CMB Retreat golden pipette, Brian Keppler (CMB alumnus), Christi Binkley, Zach Morrow, Tamara Chamberlin, Tricia Windgassen, and Tony Dawson (pictured here). Adriana Golding won best talk, Sid Jain won best poster, and the fifth year students won best talent with their dance. This year's retreat had a strong focus on professional development, bringing in CMB alumni to share their post-graduation experiences.

Congratulations to Sarah Neuman, the 2017 Exceptional Thesis Award Winner! Sarah carried out her thesis research with Dr. Arash Bashirullah in the School of Pharmacy. Her thesis is titled "Characterization of Hobbit, a novel and conserved regulator of intracellular trafficking during regulated exocytosis." The CMB Awards Committee recognized Sarah for "her bravery in exploring the functionality of several loci that were identified from genetic screens of important physiologies in Drosophila, and for her exceptional scientific perspective. Her intellectual fearlessness led to several interesting new discoveries."

CMB student and member of the Professional Development Committee Shane Bernard created a new tool to help current and prospective students understand their career opportunities after graduation. To create the tool, information was collected about alumni career development at 1, 4, and 7 years post graduation. The data was then used to map out alumni career paths. A summary of the findings can be found here. For more information on the alumni data tool, please contact the CMB Office.

CMB student and member of the Professional Development Committee Shane Bernard created a new tool to help current and prospective students understand their career opportunities after graduation. To create the tool, information was collected about alumni career development at 1, 4, and 7 years post graduation. The data was then used to map out alumni career paths. A summary of the findings can be found here. For more information on the alumni data tool, please contact the CMB Office.

CMB Trainer Yoshihiro Kawaoka has identified an influenza virus strain that is lethal and transmissible between ferrets. "This is the first case of a highly pathogenic avian virus that transmits between ferrets and kills them," he says. "That's not good for public health." Read the full story from UW News here.

Need advice on mentoring? Dr. Pamela Kreeger, CMB Trainer, and Dr. Kristyn Masters write about developing a mentor-mentee expectations document. You can read the article here.

"Nicholas R. Davenport of the Program in Cellular and Molecular Biology, University of Wisconsin, Madison, was named by the Molecular Biology of the Cell (MBoC) Editorial Board as recipient of the 26th annual MBoCPaper of the Year Award. As a graduate student in Bill Bement’s lab, Davenport was first author of the article “Membrane dynamics during cellular wound repair” (Mol. Biol. Cell 27, 2272–2285)." Excerpt from ascb.org. View the full article here.

Next Up: 
November 3, 2017at 4pm, Bock Labs Penthouse:
Josh Everson (Lipinski Lab) 
Christina Hansen (Pelegri Lab)

The time is finally here! The new CMB Transcript newsletter is published on the CMB website. We've had a busy year, and we’re excited to share some of our highlights with you. A big thank you to all who have donated their time, money, and stories to the CMB Program. You can find the 2017 Transcript by heading over to the CMB website here.

CMB alumnus Dr. Don Gillian-Daniel recently co-founded a new workshop on inclusive teaching for faculty and staff at UW-Madison. The underlying premise of the workshop is to raise awareness among faculty and staff about issues faced by marginalized students. Based on training developed at the Wisconsin Center for Education Research (WCER), it aims to teach educators how to address these problems in the classroom and normalize the conversations on campus around the sensitive topics of race, racism, power and inclusion. Dr. Gillian-Daniel received his PhD from CMB in 1997 and currently is an Associate Director with the Delta Program. Full story by WCER

The Discovery Challenge is a research competition open to UW-Madison graduate students and postdocotral researchers from all departments. The event featured a poster session and almost 60 presenters ranging from psychiatry to botany, medical informatics to civil engineeing. Cash prizes were awarded to the most creative, impactful and collaborative proposals. Sarah Neuman was awarded for her work in understanding the effect of insulin secretion on growth in mutant animals with reduced body size - A Screen for Systematic Growth Regulators Reveals Hobbit, a Novel and Conserved Regulator of Insulin Secretion. Click here for the full story. 

Congratulations to Nadia Khan, who was recently inducted into the Bouchet Graduate Honor Society. In the spirit of Dr. Edward Alexander Bouchet, membership in this society is based on students’ exemplary qualities of scholarship, leadership, character, service, and advocacy for students who have been traditionally underrepresented in the academy. Nadia will attend the induction ceremony at the Annual Yale Bouchet Conference on Diversity and Graduate Education in April 2017. See the 2016-2017 Bouchet Scholars page for more information.

The prospect of regenerating bone lost to cancer or trauma is a step closer to the clinic as University of Wisconsin-Madison scientists, including CMB trainer Wan-Ju Li, have identified two proteins found in bone marrow as key regulators of the master cells responsible for making new bone.
To read more of the article, visit: http://news.wisc.edu/uw-scientists-find-key-cues-to-regulate-bone-building-

The prospect of regenerating bone lost to cancer or trauma is a step closer to the clinic as University of Wisconsin-Madison scientists, including CMB trainer Wan-Ju Li, have identified two proteins found in bone marrow as key regulators of the master cells responsible for making new bone.
To read more of the article, visit: http://news.wisc.edu/uw-scientists-find-key-cues-to-regulate-bone-building-

The prospect of regenerating bone lost to cancer or trauma is a step closer to the clinic as University of Wisconsin-Madison scientists, including CMB trainer Wan-Ju Li, have identified two proteins found in bone marrow as key regulators of the master cells responsible for making new bone.
To read more of the article, visit: http://news.wisc.edu/uw-scientists-find-key-cues-to-regulate-bone-building-

Recent CMB alumna Asuka Eguchi led the study to reprogram cells from one type to another in a more efficient and less biased manner than previous methods. The full article can be found on the UW-Madison Department of Biochemistry website as well as an original press release on the UW-Madison News site.

CMB students gathered again this November at the Heidel House in Green Lake, WI for the annual student retreat. Congratulations to the winner for Best Talk (Adam Bayless, Bent Lab) and Best Poster (Drew Doering, Hittinger Lab). Pictured here are the winners of the coveted Golden Pipette. In addition to the usual activities, this year three CMB alumni joined the retreat to talk about their career paths.

CMB students gathered again this November at the Heidel House in Green Lake, WI for the annual student retreat. Congratulations to the winner for Best Talk (Adam Bayless, Bent Lab) and Best Poster (Drew Doering, Hittinger Lab). Pictured here are the winners of the coveted Golden Pipette. In addition to the usual activities, this year three CMB alumni joined the retreat to talk about their career paths.

Five faculty members from UW-Madison, including Ann Palmenberg and David Brow, have been elected Fellows of the American Association for the Advancement of Science (AAAS), the world's largest general scientific society.
Read the full article on the UW-Madison news website.

UW-Madison researchers, including CMB trainers John Kuo, Beth Weaver, and Paul Ahlquist, were honored for their cancer research at the October 30, 2016 Badgers men’s basketball game.
 
Photo credit: David Stluka, UW Athletics

Assistant Professor of Biology Jason Kuehner (PhD 2008) recently traveled to Beijing, China to attend the International Beijing Science Festival. As a graduate student in the CMB Program, Kuehner researched the mechanism and regulation of eukaryotic gene expression under the direction of Dr. David Brow.
 
Source: Emmanuel College News
Read the full article here.

Congratulations to Shang Ma, who won the 2015 Exceptional Thesis Award. Shang’s work in the Huang Lab involved the use of mouse models to study brain development. He is now working as a post-doc with Dr. Ardem Patapoutian, an HHMI Investigator at the Scripps Research Institute, where he is studying mechanotransduction.
 
Read the full article here. 

Congratulations to Ahna Skop, who has been honored with the 2016 UW Distinguished Teaching Award. Dr. Skop received her PhD from the CMB Program in 2000 and is currently an associate professor of genetics and a CMB faculty trainer. Dr. Skop has been a leader in advocating for student diversity and inclusiveness at UW-Madison for more than a decade. 
 
Read the full article here.

Congratulations to Ahna Skop, who has been honored with the 2016 UW Distinguished Teaching Award. Dr. Skop received her PhD from the CMB Program in 2000 and is currently an associate professor of genetics and a CMB faculty trainer. Dr. Skop has been a leader in advocating for student diversity and inclusiveness at UW-Madison for more than a decade. 
 
Read the full article here.

University of Wisconsin-Madison researchers studying monkeys have shown that one infection with Zika virus protects against future infection, though pregnancy may drastically prolong the time the virus stays in the body. The researchers, led by UW-Madison pathology Professor and CMB Trainer David O’Connor, published a study in June in the journal Nature Communications.
 
Read the full article here.

Phil Newmark, a developmental biologist studying the mysteries of how the body regenerates damaged tissue, joined the Morgridge Institute for Research and the University of Wisconsin–Madison Department of Zoology in fall 2016. He has also been appointed as a CMB trainer and will be bringing a team of about ten researchers to campus, including three new CMB students.
 
Read the full article here.

CMB student Sarah Neuman recently had the chance to interview Francis Collins, the National Institutes of Health Director and former leader of the Human Genome Project, for the blog Genes to Genomes. In the interview, Dr. Collins offers insights on the role of genetics and model organisms in the future of biomedical research and advice to early-career scientists.
 
Click here to read the full blog post.

CMB faculty, Dave Pagliarini, has received the U.S. government's highest honors for scientists who "show exceptional potential for leadership at the frontiers of scientific knowledge in the 21st century." He is 1 of 105 recipients nationally to receive the Presidential Early Career Award for Scientists and Engineers (PECASE). 
 
Click here to read more

CMB Faculty, Sean Carroll, who runs the film studio, Tangled Bank, in DC has just won an Emmy. A three part series, Your Inner Fish, airing on PBS in 2014, shows how hidden in every human body is a history of past lives before us.

Click here to read more

Or head here to watch this amazing series

CMB faculty, Ronald Raines, was awarded with the Ralph F. Hirschmann Award in Peptide Chemistry by the American Chemistry Society. Their research found that an interaction, previously discarded, is known to be a stabilizer for proteins and have applications for wound treatment in humans.
 
To read more, click here to hear more at University of Wisconsin - Madison News

CMB faculty, Dave Pagliarini, has been named as the metabolism director for the Morgridge Institute of Research. Pagliarini comes from the Department of Biochemistry at UW-Madison and is in now in charge of creating a new team of metabolic researchers at Morgridge. 
 
Follow the link here to read more at University of Wisconsin - Madison News

Congratulations to Robert Ihry and Saheed Imam, who have both won the inaugural CMB Exceptional Thesis Award! This annual award honors CMB graduate students who have written and defended outstanding theses. As part of the award, Ihry and Imam will each receive $250 and a plaque, and their names will be added to a plaque that will be housed in Bock Laboratories.
 
Click here to read the full article.

Check out some recent CMB student honors and awards. Congratulations to these students!

Attie is unpuzzling the fast growing disease of diabetes. Identifying two genes, Sorcs1 and Tomosyn-2, that have shown insight into the bodies stages of metabolism and offering potential leads for new drugs. His own mother suffering from diabetes gives Attie the motivation to solve this puzzle.
Read the rest of the article here.

Xin Sun, professor of medical genetics, was awarded with the Romnes Faculty Fellowship. This award recognizes exceptional faculty members who have earned tenure within the last six years. Her studies have uncovered the origin of birth defects and traces their progression and contributes to the development of genetic counseling, diagnosis and treatment.
Click here to read more on the article: www.news.wisc.edu/23553

CMB Chair, David Wassarman, and CMB faculty member, Barry Ganetzky are featured in a Badger Herald article that outlines the use of fruit flies to study traumatic brain injury.  Check out the article here: http://badgerherald.com/news/2014/10/27/uw-researchers-look-at-fruit-flies-to-study-traumatic-brain-injury/#.VFI2Nry26X1

A team of University of Wisconsin-Madison researchers is digging into the inner workings of the tiny cellular machines called spliceosomes, which help make all of the proteins our bodies need to function. David Brow, Samuel Butcher, and colleagues have captured images of this machine, revealing details never seen before.
 
Click here to read the full article.

A team of researchers at the University of Wisconsin-Madison, led by Yoshihiro Kawaoka, identified eight genes from influenza viruses isolated from wild ducks that possessed remarkable genetic similarities to the genes that made up the 1918 pandemic flu virus. 
 
Click here to read the full article. 

Scientists at the University of Wisconsin Carbone Cancer Center (UWCCC) report that a new class of tumor-targeting agents can seek out and find dozens of solid tumors, even illuminating brain cancer stem cells that resist current treatments.
 
Click here for the full article. 

CMB Faculty, Chris Hittinger, and his team have confirmed that Saccharomyces eubayanus, a native yeast of Patagonia, is the parent yeast of the hybrid lager yeast used to make lager or cold stored beer.
 
Click here to read the article featured on University of Wisconsin - Madison News. 

 

 

Ann Palmenberg, Professor of biochemistry at UW-Madison and CMB faculty member, and her team, which includes CMB student, Holly Basta, have constructed a three-dimensional model of the pathogen that shows why there is no cure yet for the common cold. Palmenberg and her team have published their findings in the journal Virology.  Check out the article here and learn more! 

Ann Palmenberg, Professor of biochemistry at UW-Madison and CMB faculty member, and her team, which includes CMB student, Holly Basta, have constructed a three-dimensional model of the pathogen that shows why there is no cure yet for the common cold. Palmenberg and her team have published their findings in the journal Virology.  Check out the article here and learn more! 

For the first time, scientists have transplanted neural cells derived from a monkey's skin into its brain and watched the cells develop into several types of mature brain cells, according to the authors of a new study in Cell Reports, including CMB faculty member Su-Chun Zhang. After six months, the cells looked entirely normal, and were only detectable because they initially were tagged with a fluorescent protein.
Read more here.

 Photo: Jeff Miller, UW Communications

Congrats to Penny Lam, CMB student in Anna Huttenlocher's lab, who was recently selected as one of ten winning pictures in the 2013 Cool Science Photo Contest at UW-Madison. The selected picture is the neuronal network in the tail fin of a live zebrafish embryo magnified 40 times. Read the full article and see the other winning pictures here

Researchers at the University of Wisconsin Carbone Cancer Center, led by CMB faculty Mark Burkard, have discovered a new form of cell division in human cells. They believe it serves as a natural back-up mechanism during faulty cell division, preventing some cells from going down a path that can lead to cancer.
 
Check out the full UW news story: http://www.news.wisc.edu/21364

With metabolically engineered microorganisms hungry for levulinic acid rather than sugar, a UW-Madison chemical and biological engineer aims to create more sustainable, cost-effective processes for converting biomass into high-energy-density hydrocarbon fuels. Watch a video about Pfleger's work with next generation biofuels at here.
 
Read the full article here.

For babies, the trip from the womb to the outside world is a transition from a blank, sterile slate to host for what will eventually be trillions of microscopic organisms. "While that microbial environment in the gut is still developing, the introduction of one of many of the wrong kinds of bacteria may cause a severe immune response," says Douglas Weibel, biochemistry professor at UW-Madison. 
Read the full article here

CMB Faculty Trainer, Doug Weibel

Congratulations to two outstanding new faculty trainers in CMB who were recently named Shaw Scientists by the Greater Milwaukee Foundation!  Both Dr. Mehle and Dr. Pagliarini are currently training CMB grad students in their labs.  Read the full UW news article here: http://www.news.wisc.edu/20736

Dr. Mehle on the left, Dr. Pagliarini on the right.

University of Wisconsin-Madison biochemist Judith Kimble has been selected to serve on President Obama's Committee on the National Medal of Science.
Read more here

CMB student Brittany Jacobs, lab member in Troy Hornberger's lab, receives honorable mention in the 2012 Cool Science Image Contest. Read more about Brittany's image here.

On a beautiful summer day in Madison, the Kalejta lab poses for a new lab photo.  What a fun idea!  They study the replication and pathogenesis of the beta-herpesvirus called Human Herpesvirus Type 5 (HHV-5) or Human Cytomegalovirus (HCMV).  More information about their lab can be found  here: http://kalejta.virology.wisc.edu/

A recent article by CALS Communications Program member, Nicole Miller, focuses on the use of Amoeba biotherapy in the Filutowicz lab.  The full article is available on the UW-Madison CALS News page.

CMB faculty trainer and alumni, Grace Boekhoff-Falk is featured for her work on fruit flies and how they detect the sense of smell.  The full article can be found on the UW-Madison School of Medicine and Public Health website.

CMB faculty trainer and alumni, Grace Boekhoff-Falk is featured for her work on fruit flies and how they detect the sense of smell.  The full article can be found on the UW-Madison School of Medicine and Public Health website.

Chris Pfund is currently the Associate Director for the UW-Madison DELTA Program, which promotes the development of a future national faculty in the natural and social sciences, engineering, and mathematics. Chris continues to share her talents with the CMB Program through professional development workshops for faculty mentor training and first year grad students.   

The research projects in our laboratory are focused on molecular imaging, molecular therapy, and nanotechnology. Molecular medicine is the future of 21st century patient management. Molecular imaging, the visualization, characterization and measurement of biological processes, can play pivotal roles in disease diagnosis, treatment efficacy assessment, drug discovery, and the understanding of fundamental biology.

Interests include HIV/SIV genetics, virology, immunology, and pathogenesis. Lab Website.
 

The Jorgensen lab uses cell and molecular biology tools to identify genes that are sexually dimorphic during sex differentiation, characterize their functional significance, and finally, understand how they are regulated.  Currently, we are focusing on two genes: steroidogenic factor 1 (Sf1) and Iroquois homeobox factor 3 (Irx3).

The Smith group is an interdisciplinary group of researchers working on the development of novel methods and approaches for the analysis and manipulation of bio-molecules. Major interest areas include biological mass spectrometry, DNA computing, surface chemistry, surface detection methods (fluorescence, surface plasmon resonance), and the analysis of genetic variations.

The research projects in the Raines laboratory are designed to reveal how biological phenomena can be explained with the principles of chemistry. The hypotheses are far-reaching, and testing them requires the use of techniques and ideas from diverse disciplines. This broad/deep training is appropriate for scientists who want to perform innovative and meaningful research at the widening chemistry - biology interface.

Dr. Burkard is interested in targeted therapy directed at protein kinases. His laboratory seeks to link therapies with their targets within cancer cells using genetic tools, and to identify patients whose cancers are most likely to benefit from particular drugs. These studies will be used to inform clinical development of novel agents. Dr. Burkard is part of the breast cancer disease oriented working group.

Why do we get sick? This simple question underpins all research in my laboratory. Our overarching goal is to understand why immune responses sometimes fail to protect us from acute and chronic viral diseases. We study innate and adaptive immune responses to acute and chronic viral infections and the mechanisms viruses have evolved to subvert them. Through our discoveries, we hope to contribute to the campaigns against pandemic influenza and AIDS.

Michael works on the discovery and characterization of novel pathogens in African non-human primates as well as studies intra-host variability in Hepatitis C virus and Dengue virus.  Michael joined CMB in the fall of 2009 and is originally from Germany.   

CMB Student, Maria Mikedis (Karen Downs Lab) was selected and recently attended the 61st annual meeting of Nobel Laureates in Lindau, Germany. She was selected from an internal UW competition and then a national selection. Based on her thesis advisor holding an NIH grant, Maria's exciting research topic and high productivity within a short period of time, Maria was selected to represent research.
 

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Applying to CMB

The application for Fall 2018 admission is now closed. The application deadline for Fall 2019 admission will be December 1, 2018. Information about how to apply, admissions suggestions, and much more can be found under the Prospective Students section of the website.