Photo: Golgi outposts illuminated in the dendrites of a sensory neuron illustrate the polarized distribution of the secretory system in neurons. (Mike Kelliher)
The cell is the fundamental unit of life, making it essential to understand how cells divide, function, and signal. Disruption of these primary cellular processes has been associated with tumor development as well as aberrant cell and tissue function in human disease. Cell Adhesion & Cytoskeleton focus group members investigate topics ranging from cell division to cytoskeletons to signaling to migration. Our members leverage a variety of cutting-edge cross-disciplinary approaches that combine cell biology with innovative biochemistry, genetics, molecular biology, and microscopy techniques. The integration of these sophisticated approaches enables multiscale insight into how cells work. In their research, members use cells in culture and model organisms, including zebrafish, mice, and fruit flies. Madison has a rich tradition of collaborative research. Reflecting this, there are several campus-wide group meetings that bring together Cell Adhesion & Cytoskeleton members and other researchers interested in cell biology. These include the weekly Cell Biology Study Group (CBSG) and the Cell Division meeting (https://cytoskeletonatmadison.weebly.com/).